The Rabbit Anti-BTK Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Bruton Tyrosine Kinase, and BTK. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-BTK Antibody has been shown to work in the following applications: Other.
Description
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK