The Rabbit Anti-PTPN11 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to protein tyrosine phosphatase non-receptor type 11, and PTPN11. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-PTPN11 Antibody has been shown to work in the following applications: Immunofluorescence, and Immunohistochemistry.
Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
This product can be used in analytical tools such as IHC, Immunofluorescence