The [KO Validated] GANAB Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GANAB. This antibody recognizes Human, Mouse, and Rat antigen. The [KO Validated] GANAB Rabbit pAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease