The Phospho-EGFR (Y1086) Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to EGFR, and epidermal growth factor receptor. This antibody recognizes Human antigen. The Phospho-EGFR (Y1086) Rabbit pAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysosomal degradation. Phospho-EGF Receptor (Tyr1086) Antibody is directed against a previously unpublished EGF receptor phosphorylation site at Tyr1086, Phosphorlation of EGF receptor at Tyr1086 was observed in select carcinoma cell lines and in tumors