MyBioSource.com's Rabbit Anti-VAMP2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Rabbit Anti-VAMP2 Antibody was generated using VAMP2 as the antigen and it reacts with Human.
Description
Vesicle-associated membrane protein 2 (VAMP2), a member of soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNAREs) is required for membrane fusion. The transmembrane domains (TMDs) of VAMP2 plays a critical role in membrane fusion and that the structural mobility provided by the central small amino acids is crucial for exocytosis by influencing the molecular re-arrangements of the lipid membrane that are necessary for fusion pore opening and expansion. Moreover, VAMP2 is the main vesicle associated membrane protein (VAMP) isoform functionally involved in antibody secretion