MyBioSource.com's Rat Anti-CD3 Antibody is a Rat monoclonal antibody. The Rat Anti-CD3 Antibody was generated using CD3D as the antigen. It reacts with Mouse. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3epsilon, delta, gamma and zeta chains. It forms a TCR complex by associating with TCR alpha/beta or gamma/delta chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex