MyBioSource.com's Anti-Ms CD86 FITC is a Rat monoclonal antibody. The Anti-Ms CD86 FITC Antibody was generated using CD86 as the antigen. It reacts with Mouse. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response