The Rabbit Anti-HNMT Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Hnmt. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-HNMT Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
This product can be used in analytical tools such as Western Blot, IHC