The TP63 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TP63, and tumor protein p63. This antibody recognizes Human, Mouse, and Rat antigen. The TP63 Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Immunohistochemistry.
Description
TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40), 50kd(P60), 63kd(P63) and 73kd(P73L). It is Nuclear stain