MyBioSource.com's Rabbit Anti-c-Jun Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-c-Jun Antibody was generated using JUN as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunoprecipitation, and Western Blot.
Description
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed: 24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed: 24623306)