The Phospholipase A2 Activator Protein Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to PLAA. This antibody recognizes Human antigen. The Phospholipase A2 Activator Protein Rabbit mAb Antibody has been shown to work in the following applications: Western Blot.
Description
Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (PubMed:27753622). Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:18291623, PubMed:28007986)