The CREB Regulated Transcription Coactivator 2 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to Crtc2. This antibody recognizes Human, and Rat antigen. The CREB Regulated Transcription Coactivator 2 Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)