The TMEM173 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to stimulator of interferon response cGAMP interactor 1, and STING1. This antibody recognizes Human, Mouse, and Rat antigen. The TMEM173 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants