MyBioSource.com's Rabbit Anti-UNC13B Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Western Blot. The Rabbit Anti-UNC13B Antibody was generated using unc-13 homolog B as the antigen and it reacts with Human, and Mouse.
Description
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
This product can be used in analytical tools such as Western Blot, Immunofluorescence