The Rabbit Anti-TRF1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TERF1. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-TRF1 Antibody has been shown to work in the following applications: Western Blot.
Description
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double- stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways