The Rabbit Anti-ASPSCR1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ASPSCR1, and ASPSCR1 tether for SLC2A4, UBX domain containing. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-ASPSCR1 Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.
This product can be used in analytical tools such as Western Blot, IHC, Immunofluorescence