The Rabbit Anti-Eps15 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Eps15. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Eps15 Antibody has been shown to work in the following applications: Western Blot.
Description
Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Plays a role in the assembly of clathrin-coated pits (CCPs). Acts as a clathrin adapter required for post-Golgi trafficking. Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta- 1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2