The PRDM2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PR/SET domain 2, and PRDM2. This antibody recognizes Rat antigen. The PRDM2 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene