MyBioSource.com's ACMSD Conjugated Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Other. The ACMSD Conjugated Antibody was generated using ACMSD as the antigen and it reacts with Human.
Description
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS