MyBioSource.com's Anti-Mouse CD25 APC is a Rat monoclonal antibody. It reacts with Mouse. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor alpha chain (IL-2R alpha), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor beta) and CD 132 (IL-2 Receptor gammac, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2Ralpha. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.
The PC61.5 antibody blocks the binding of IL-2 to both high-affinity and low-affinity receptors