The Angiopoietin 2 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to Angiopoietin 2, and ANGPT2. This antibody recognizes Human, Mouse, and Rat antigen. The Angiopoietin 2 Rabbit mAb Antibody has been shown to work in the following applications: Western Blot.
Description
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal