MyBioSource.com's Wnt-1 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The Wnt-1 Polyclonal Antibody was generated using Wnt family member 1, and WNT1 as the antigen and it reacts with Human, and Mouse.
Description
Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (PubMed:26902720, PubMed:28528193, PubMed:23656646). In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (By similarity). Plays an essential role in the development of the embryonic brain and central nervous system (CNS)(By similarity). Has a role in osteoblast function, bone development and bone homeostasis (PubMed:23656646)