The VPS35 Antibody, Clone 8A3: RPE from MyBioSource.com is a Mouse Monoclonal antibody to VPS35. This antibody recognizes Human, Mouse, and Rat antigen. The VPS35 Antibody, Clone 8A3: RPE has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson's Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3)