The Phospho-c-Jun (Ser63) Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to JUN. This antibody recognizes Human, Mouse, and Rat antigen. The Phospho-c-Jun (Ser63) Rabbit pAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed: 24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed: 24623306)