MyBioSource.com's Rabbit Anti-Calreticulin Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, and Immunofluorescence. The Rabbit Anti-Calreticulin Antibody was generated using CALR, and Calreticulin as the antigen and it reacts with Human, Mouse, and Rat.
Description
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity)