The Rabbit Anti-BCL6 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BCL6, and BCL6 transcription repressor. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-BCL6 Antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
This product can be used in analytical tools such as Western Blot, Immunofluorescence