The MCM6 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MCM6. This antibody recognizes Human, Mouse, and Rat antigen. The MCM6 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity