MyBioSource.com's HIST1H2AB Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Immunohistochemistry. The HIST1H2AB Antibody was generated using H2A clustered histone 4, H2A clustered histone 8, H2AC4, and H2AC8 as the antigen and it reacts with Human.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling