MyBioSource.com's Anti-CEA [BW431/26], Rabbit IgG is a Rabbit monoclonal antibody. The Anti-CEA [BW431/26], Rabbit IgG Antibody was generated using CEA cell adhesion molecule 5, and CEACAM5 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: In Vivo Imaging.
Description
Technetium 99-labeled (Tc-99m) BW431/26 has been used in the identification and detection of colorectal carcinomas, breast cancers, bladder carcinomas, lung adenocarcinomas and their recurrences by immunoscintigraphy (PMID: 2602902, 2662074, 2685692, 2297747, 2157833, 2166552, 2383485, 1984945). The use of Tc-99m-BW 431/26 immunoconjugates in immunoscintigraphy resulted in reduction of radiation dose for the patient down to 5% of the dose applied as compared with I-131 labelled MAbs (PMID: 3262953). Humanized version of this antibody also shows similar binding affinity as compared to its murine parent antibody (PMID: 1762576)