The Rabbit Anti-Casein Kinase Ialpha Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CSNK1A1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Casein Kinase Ialpha Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688)