MyBioSource.com's Rabbit Anti-BCL-XL Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Other. The Rabbit Anti-BCL-XL Antibody was generated using BCL2 like 1, and BCL2L1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X (S) promotes apoptosis