The Anti-Hu CD42b APC Antibody from MyBioSource.com is a Mouse Monoclonal antibody to GP1BA. This antibody recognizes Human antigen. The Anti-Hu CD42b APC Antibody has been shown to work in the following applications: Flow Cytometry.
Description
CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis