MyBioSource.com's Ubiquityl-Histone H2A-K119 Rabbit pAb is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Ubiquityl-Histone H2A-K119 Rabbit pAb Antibody was generated using H2A clustered histone 4, H2A clustered histone 8, H2AC4, and H2AC8 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.H2A clustered histone (H2AC) consists of several H2A family members, which function as replication-dependent histone proteins