The Phospho-EGFR (Y1173) Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to EGFR, and epidermal growth factor receptor. This antibody recognizes Human antigen. The Phospho-EGFR (Y1173) Rabbit pAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysosomal degradation. The GRB2 adaptor protein binds activated EGFR at phospho-Tyr1068