MyBioSource.com's Anti-LCRMP4, 2H7 is a Mouse monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, and ELISA.
Description
Mouse monoclonal antibody against the long isoform of human Collapsin Response Mediator Protein 4 (LCRMP4), Clone 2H7. Mouse monoclonal antibody against the long isoform of human Collapsin Response Mediator Protein 4 (LCRMP4).
CRMP4 belongs to the collapsin response mediator protein (CRMP) family that includes CRMP 1-5. CRMPs are highly expressed in the nervous system during brain development. It is also found that CRMP4 is inversely associated with lymph node metastasis of prostate cancers and that the methylation of the CpG island within the promoter region of CRMP4 gene down- regulates CRMP4 expression (Xin Gao et al. 2010; Ke Li et al. 2015). Recently, Dr. Xin Gao's lab found that a long-form CRMP4 (LCRMP4) is potentially useful as a serum biomarker for prostate cancers