The Rabbit Anti-ANTXR1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ANTXR1. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-ANTXR1 Antibody has been shown to work in the following applications: Immunofluorescence.
Description
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
This product can be used in analytical tools such as Immunofluorescence