The MIP-1beta Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to C-C motif chemokine ligand 4 like 1, CCL4, and CCL4L1. This antibody recognizes Human antigen. The MIP-1beta Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B