The Anti-DKK1 antibody (DM210), Rabbit mAb from MyBioSource.com is a Rabbit Monoclonal antibody. This antibody recognizes Human antigen. The Anti-DKK1 antibody (DM210), Rabbit mAb has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Flow Cytometry.
Description
This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines