The PRMT2 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PRMT2. This antibody recognizes Human antigen. The PRMT2 antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
Rabbit anti Human PRMT2 antibody recognizes protein arginine N-methyltransferase 2.
PRMT2 methylates arginyl residues in proteins such as STAT3, FBL, histone H4 and functions as a coactivator of androgen receptor (AR)-mediated and estrogen receptor (ER)-mediated transactivation (Qi et al. 2002, Meyer et al. 2007). PRMT2 may inhibit NF-kappa-B transcription and promote apoptosis involved in growth regulation (Ganesh et al. 2006). In humans, the C-terminal domain of pol II (CTD) comprises 52 repeats of the consensus heptapeptide Tyr1/Ser2/Pro3/Thr4/Ser5/Pro6/Ser7 that is phosphorylated by several kinases during transcription