WNK4 Antibody - BSA Free NB600-284 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemWNK4 Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $419.00Supplier Page View Company Product Page
Catalog NumberNB600-284
NCBI Gene AliasesPRKWNK4, PHA2B
ImmunogenA synthetic peptide made to a region of the human WNK4 protein between residues 200-300. [UniProt# Q96J92]
Concentration1.0 mg/ml
ApplicationsIF/IHC,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Electron Microscopy
HostRabbit
Quantity0.1 ml (also 0.025 ml)
FormatPBS
TargetWNK4
ReactivityHuman,Mouse,Rat
Conjugate/TagUnconjugated
NCBI Full Gene NameWNK lysine deficient protein kinase 4
ClonalityPolyclonal
PurityImmunogen affinity purified
Research AreaCell Biology, Potassium Channels, Protein Kinase, Signal Transduction
IsotypeIgG
Antibody TypePrimary Antibodies
StorageAliquot and store at -20C or -80C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Sizes Available: 0.1 ml (also 0.025 ml)

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Evidence for functional regulation of the KLHL3/WNK pathway by O-GlcNAcylationGlycobiologyAugust 11, 2025Jimin Hu, Duc T. Huynh, Denise E. Dunn, Jianli Wu, Cindy Manriquez-Rodriguez, Qianyi E. Zhang, Gabrielle A. Hirschkorn, Tetsuya Hirata, George R. Georgiou, Samuel A. Myers, et al.sc-47724",1:2000 WNK4 (for WB),"Cell Signaling Technology, 5713",1:1000 WNK4 (for IF),"Novus Biologicals, NB600–284",1:400 Goat HRP-conjugated anti-mouse IgG secondary antibody,"SouthernBiotech, 1030–05","1:5000, 1:10000" Goat

(2) Evidence for Functional Regulation of the KLHL3/WNK Pathway by O-GlcNAcylationbioRxivMarch 1, 2025Jimin Hu, Duc T. Huynh, Denise E. Dunn, Jijanli We, Cindy Manriquez-Rodriguez, Qianyi E. Zhang, Gabrielle A. Hirschkorn, George R. Georgiou, Tetsuya Hirata, Samuel A. Myers, et al.sc-47724",1:2000 WNK4 (for WB),"Cell Signaling Technology, 5713",1:1000 WNK4 (for IF),"Novus Biologicals, NB600-284",1:400 Goat HRP-conjugated anti-mouse IgG secondary antibody,"SouthernBiotech, 1030-05","1:5000, 1:10000" Goat

(3) Pathophysiological roles of WNK kinases in the kidneyPflugers Archiv : European journal of physiologySeptember 1, 2010Uchida S.

(4) Gender difference in kidney electrolyte transport. I. Role of AT_1a receptor in thiazide-sensitive Na⁺-Cl^- cotransporter activity and expression in male and female miceAmerican journal of physiology. Renal physiologyJanuary 1, 0001"Li J, Hatano R, Xu S, Wan L, Yang L, Weinstein AM, Palmer L, Wang T."

(5) WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interactionThe Journal of biological chemistryJanuary 1, 0001"Subramanya AR, Liu J, Ellison DH, Wade JB, Welling PA."

(6) FGF23 promotes renal calcium reabsorption through the TRPV5 channelThe EMBO journalJanuary 1, 0001"Andrukhova O, Smorodchenko A, Egerbacher M, Streicher C, Zeitz U, Goetz R, Shalhoub V, Mohammadi M, Pohl EE, Lanske B, et al."

(7) Melatonin modulates nitric oxide-regulated WNK-SPAK/OSR1-NKCC1 signaling in dorsal raphe nucleus of ratsThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of PharmacologyJanuary 1, 0001"Yang HJ, Kim MJ, Kim SS, Cho YW."A301-877A, respectively; Bethyl Laboratories Inc., Montgomery, TX, USA), anti-WNK2, anti-WNK4 (25910002 and NB600-284, respectively; Novus Biologicals, Littleton, CO, USA), anti-TPH2, anti-SPAK (ab111828 and ab79045, respectively;

(8) WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive ratsJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismJanuary 1, 0001"Bhuiyan MIH, Song S, Yuan H, Begum G, Kofler J, Kahle KT, Yang SS, Lin SH, Alper SL, Subramanya AR, et al."

(9) "Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats"American journal of physiology. Renal physiologyJanuary 1, 0001"Song J, Hu X, Riazi S, Tiwari S, Wade JB, Ecelbarger CA."

(10) Generation of WNK1 knockout cell lines by CRISPR/Cas-mediated genome editingAmerican journal of physiology. Renal physiologyJanuary 1, 0001"Roy A, Goodman JH, Begum G, Donnelly BF, Pittman G, Weinman EJ, Sun D, Subramanya AR."

(11) CFTR plays an important role in the regulation of vascular resistance and high-fructose/salt-diet induced hypertension in miceJournal of cystic fibrosis : official journal of the European Cystic Fibrosis SocietyJanuary 1, 0001"Zhang YP, Ye LL, Yuan H, Duan DD."

(12) Sympathetic regulation of NCC in norepinephrine-evoked salt-sensitive hypertension in Sprague-Dawley ratsAmerican journal of physiology. Renal physiologyJanuary 1, 0001"Frame AA, Puleo F, Kim K, Walsh KR, Faudoa E, Hoover RS, Wainford RD."

(13) WNK4 regulates apical and basolateral Cl- flux in extrarenal epitheliaProceedings of the National Academy of Sciences of the United States of AmericaJanuary 1, 0001"Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP."

(14) NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stressScience advancesJanuary 1, 0001"Amnekar RV, Dite T, Lis P, Bell S, Brown F, Johnson C, Wilkinson S, Raggett S, Dorward M, Wightman M, et al."cross-react with NKCC1 Thr212); anti-NRBP1: SAB1408678 (Sigma-Aldrich, rabbit polyclonal, 1:1000); anti-WNK4: NB600-284 (Novus Biologicals, rabbit polyclonal, 1:2000); anti-HA (hemagglutinin): Roche 3F10 (rat monoclonal,

(15) Immunolocalization of WNK4 in mouse kidneyHistochemistry and cell biologyJanuary 1, 0001"Ohno M, Uchida K, Ohashi T, Nitta K, Ohta A, Chiga M, Sasaki S, Uchida S."

(16) High frequency and wide range of human kidney papillary crystalline plugsUrolithiasisJanuary 1, 0001"Huguet L, Le Dudal M, Livrozet M, Bazin D, Frochot V, Perez J, Haymann JP, Brocheriou I, Daudon M, Letavernier E."a lesser extent, collecting ducts were immunostained with rabbit anti-WNK 4 antibody (1:400, clone NB600-284, Novus Bio). Collecting ducts were immunostained with a goat anti-aquaporin 2 (AQP2) antibody (1:200,

(17) Role of nitric oxide and WNK-SPAK/OSR1-KCC2 signaling in daily changes in GABAergic inhibition in the rat dorsal raphe neuronsNeuropharmacologyJanuary 1, 0001"Kim MJ, Yang HJ, Kim Y, Kang I, Kim SS, Cho YW."

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WNK4 Antibody - BSA Free

WNK4 Antibody - BSA Free

WNK4 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (17)

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WNK4 Antibody - BSA Free from Novus Biologicals, a Bio-Techne Brand

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