Fc gamma RIII (CD16) Antibody (3G8) [PerCP] NBP3-21452PCP from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemFc gamma RIII (CD16) Antibody (3G8) [PerCP]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $599.00Supplier Page View Company Product Page
Catalog NumberNBP3-21452PCP
Antibody TypePrimary Antibodies
ClonalityMonoclonal
ReactivityBaboon,Chimpanzee,Cynomolgus Monkey,Human,Rhesus Macaque
FormatPBS
ApplicationsFlow Cytometry,Immunohistochemistry,Immunoprecipitation,Block/Neutralize,Surface Plasmon Resonance (SPR),Immunocytochemistry/ Immunofluorescence
Clone3G8
Quantity0.1 ml
ImmunogenHuman PMN (polymorphonuclear leukocytes) cells
TargetFc gamma RIII (CD16)
IsotypeIgG Kappa
Conjugate/TagPerCP
HostRabbit
PurityProtein A purified
StorageStore at 4C in the dark
NCBI Full Gene NameFc gamma receptor IIIa
NCBI Gene AliasesCD16, CD16-II, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, FcGRIIIA, IGFR3, IMD20

Specifications/Features

Available conjugates: Available conjugates: PerCP, mFluor Violet 500 SE

Specificity: This antibody binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity).

Sizes Available: 0.1 ml

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