Description
Product Characteristics:
Aliases: HSMT 3 antibody, HSMT3 antibody, MGC117191 antibody, Sentrin 2 antibody, Sentrin-2 antibody, Sentrin2 antibody, Small ubiquitin like modifier 2 antibody, Small ubiquitin related modifier 2 antibody, Small ubiquitin-related modifier 2 antibody, SMT 3B antibody, SMT3 homolog 2 antibody, SMT3 suppressor of mif two 3 homolog 2 antibody, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) antibody, SMT3, yeast, homolog 2 antibody, Smt3A antibody, SMT3B antibody, SMT3H2 antibody, SUMO-2 antibody, SUMO-3 antibody, SUMO2 antibody, SUMO2_HUMAN antibody, Sumo3 antibody, Ubiquitin like protein SMT3B antibody, Ubiquitin-like protein SMT3A antibody
Target Information: SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM, Mar 2008]