Description
Product Characteristics:
Aliases: C21KG antibody, G 22K antibody, G-22K antibody, GTP binding protein smg p21A antibody, GTP-binding protein smg p21A antibody, KREV 1 antibody, KREV1 antibody, OTTHUMP00000013741 antibody, RAP 1A antibody, RAP1 antibody, RAP1A antibody, RAP1A member of RAS oncogene family antibody, RAP1A_HUMAN antibody, Ras related protein Krev 1 antibody, Ras related protein Rap 1A antibody, RAS related protein RAP1A antibody, Ras-related protein Krev-1 antibody, Ras-related protein Rap-1A antibody, SMGP21 antibody
Target Information: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]