Description
Product Characteristics:
Aliases: g enriched in brain 2, formerly antibody, GTP binding protein Rheb antibody, GTP-binding protein Rheb antibody, MGC111559 antibody, Ras homolog enriched in brain 2 antibody, Ras homolog enriched in brain antibody, RHEB 2 antibody, Rheb antibody, RHEB_HUMAN antibody, RHEB2 antibody, RHEB2, formerly antibody
Target Information: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]