Description
Product Characteristics:
Aliases: GAP1m antibody, GTPase activating protein of RAS antibody, Ras GTPase activating protein 2 antibody, Ras GTPase-activating protein 2 antibody, RAS p21 protein activator 2 antibody, Rasa2 antibody, RASA2_HUMAN antibody
Target Information: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein\, a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008]