Description
Product Characteristics:
Aliases: FLJ43552 antibody, G protein signaling 6 regulator antibody, GAP antibody, GTPase activating protein antibody, MGC142132 antibody, Regulator of G protein signaling 6 antibody, Regulator of G protein signalling 6 antibody, Regulator of G-protein signaling 6 antibody, RGS 6 antibody, RGS6 antibody, RGS6_HUMAN antibody, S914 antibody
Target Information: This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]