Description
Product Characteristics:
Aliases: ibody, Fox 1 homologue antibody, Fox-1 homolog B antibody, FOX2 antibody, FXH antibody, Hexaribonucleotide-binding protein 2 antibody, HNRBP2 antibody, RBFOX2 antibody, Repressor of tamoxifen transcriptional activity antibody, RFOX2_HUMAN antibody, RNA binding motif protein 9 antibody, RNA binding protein 9 antibody, RNA binding protein fox-1 homolog 2 antibody, RNA-binding motif protein 9 antibody, RNA-binding protein 9 antibody, RTA antibody
Target Information: This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]