Description
Product Characteristics:
Aliases: E3 ubiquitin-protein ligase RNF6 antibody, Ring finger protein (C3H2C3 type) 6 antibody, Ring finger protein 6 antibody, RING H2 protein antibody, RING H2 protein RNF6 antibody, RNF 6 antibody, RNF6 antibody, RNF6_HUMAN antibody, SPG2 antibody
Target Information: The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008]