Description
Product Characteristics:
Aliases: Blood group Rh(D) polypeptide antibody, Blood group--Rhesus system D polypeptide antibody, CD240D antibody, D antigen (DCS) antibody, DIIIc antibody, MGC165007 antibody, RH antibody, Rh blood group antigen Evans antibody, Rh blood group D antigen antibody, Rh polypeptide 2 antibody, RH30 antibody, Rh4 antibody, RHCED antibody, Rhd antibody, RHD_HUMAN antibody, RhDCw antibody, RHDel antibody, RHDVA(TT) antibody, Rhesus blood group D antigen allele DIII type 7 antibody, Rhesus D antigen antibody, Rhesus system D polypeptide antibody, RhII antibody, RhK562-II antibody, RhPI antibody, RHPII antibody, RHXIII antibody
Target Information: The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]