Description
Product Characteristics:
Aliases: G1/S transition control protein binding protein RbAp46 antibody, Histone acetyltransferase type B subunit 2 antibody, Histone binding protein RBBP7 antibody, Histone-binding protein RBBP7 antibody, MGC138867 antibody, MGC138868 antibody, Nucleosome remodeling factor subunit RBAP46 antibody, Nucleosome-remodeling factor subunit RBAP46 antibody, RBAP46 antibody, RBBP 7 antibody, RBBP-7 antibody, RBBP7 antibody, RBBP7_HUMAN antibody, Retinoblastoma binding protein 7 antibody, Retinoblastoma binding protein p46 antibody, Retinoblastoma-binding protein 7 antibody, Retinoblastoma-binding protein p46 antibody, Retinoblastoma-binding protein RbAp46 antibody
Target Information: This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]